Guardian root stock is tolerant of a wide range of diseases such as bacterial canker, ring nematodes and root-knot nematodes. As such it is a good choice for any orchard that will be replanted on the site of an old orchard. However, it's vigor is almost identical to that of Kakamas, and it's production is almost equal to that of kakamas in low chill zones or sandy soils. It is also very sensitive to high pH conditions.